Blog & Research
Evidence-based guides, research summaries and patient perspectives
How to Talk to Your Doctor About Ibogaine
Prepare for a medical conversation about ibogaine: treatment goals, records, medication questions, evidence, alternatives and follow-up care.
Repeat Ibogaine Treatment and Booster Doses: Evidence and Risks
What research does and does not show about repeat ibogaine treatment and booster doses, including cardiac risks and questions for providers.
How to Evaluate Ibogaine Research and Clinical Studies
A framework for reading ibogaine research: study design, who was studied, denominators behind percentages, and why registration isn't a result.
Ibogaine and Antidepressants: Why Medication Review Matters
Understand the evidence on ibogaine and antidepressants: CYP2D6, QT effects, serotonergic concerns and why stopping medication needs clinical oversight.
Ibogaine and the Risk of Mania or Psychosis: Evidence and Warning Signs
What case reports show about mania and psychosis after ibogaine, what remains unknown, and which changes call for psychiatric or emergency assessment.
Ibogaine and Benzodiazepines: Dependence, Withdrawal, and Safety Risks
What ibogaine research does not establish about benzodiazepine withdrawal, why abrupt stopping can be dangerous, and what to discuss with a clinician.
Does a Normal ECG Make Ibogaine Safe?
A normal ECG cannot guarantee ibogaine safety. Learn what baseline QTc shows, why drug effects change the picture and what to ask about monitoring.
Ibogaine's Neurological and Psychological Effects: What Is Known
Separate ibogaine's acute perceptual effects, ataxia, cognitive findings and psychiatric concerns, with clear limits on what research can establish.
Federico Fiuzzi's 2011 Ibogaine Death in Slovenia: New Details from Court Records
Ibogaine Club contacted the District Court in Maribor about Federico Fiuzzi's 2011 ibogaine death. The court confirmed a 2013 investigation request was withdrawn and criminal proceedings never opened.
Gabon and Ambio Life Sciences Discuss Iboga Partnership. What Will It Mean for Local Communities?
Gabon and Ambio Life Sciences are exploring a partnership around iboga. But will local communities, researchers, and traditional knowledge holders have a meaningful role in the industry’s future, or will most of the value continue to flow abroad?
Ibogaine Success Rates: What Published Studies Actually Measure
There is no single reliable ibogaine success rate. Here's what withdrawal relief, abstinence, and follow-up numbers in the published research actually measure, and what they don't.
Iboga vs Ibogaine: The Plant Is Not the Same as the Dose
Iboga is the plant. Ibogaine is one alkaloid inside it, at a concentration nobody can estimate by looking.
Buying Raw Iboga Root Bark Online: What You Are Actually Getting
A gram of iboga root bark from one seller is not the same dose as a gram from another. Lab data shows why that gap can be fatal.
Where Iboga Came From: 26 Versions of One Myth
A woman reaches into a river hole chasing a catfish and pulls out her dead husband's bones instead. What happens next became the founding myth of Fang Bwiti, told in at least 26 documented versions that disagree with each other on almost everything except what matters most.
Who Is NOT a Candidate for Ibogaine Treatment?
Cardiac conditions, certain medications, liver disease, psychiatric history - the absolute and relative contraindications, explained without jargon.
Iboga Never Works Alone: The Plants That Surround Every Bwiti Ceremony
Palm wine fortified with bitter bark, kola nuts passed hand to hand, cannabis some branches call a fourth sacrament, and a second visionary plant Western botanists misidentified for nearly a century. Iboga never worked in isolation.
Discovering Bwiti: The First Written Record of a Ceremony, 1865
In 1865 an explorer sat through a Bwiti ceremony he found tedious and wrote it down anyway. That bored, half-honest account is the oldest surviving eyewitness record of the tradition, and it reveals how much of the early written history of Bwiti has been silently rewritten in translation.
The Persecution of Bwiti: Gabon and Equatorial Guinea, 1930-1950
For two decades, missionaries and colonial administrators in Gabon and Spanish Guinea ran a coordinated campaign to destroy Bwiti, using raids, torture, and executions justified by a cannibalism myth nobody could ever actually prove. This is the documented history, with names, dates, and court records.
Ibogaine Aftercare & Integration: The 30, 60 and 90 Days After Treatment
The session opens a window. What you do in the weeks and months after determines whether the changes last.
Gabon Moves to Restrict Iboga Exports While Building a Domestic Framework
Gabon is tightening controls on iboga, with a May 2026 decree regulating its use and traditional knowledge and a September draft decree proposing a full export ban on the plant and all its derivatives.
Tabernanthalog (TBG) vs. Ibogaine: What the Research Shows So Far
Tabernanthalog (TBG, DLX-007) is a synthetic ibogaine analog designed to keep the therapeutic signal and drop the hallucinogenic ordeal and cardiac risk. Here's the real receptor data, what the animal studies show, where Delix Therapeutics' clinical program actually stands in 2026, and how TBG stacks up against ibogaine itself.
Louisiana Is Funding Ibogaine Trials With Opioid Settlement Money. The Law Doesn't Require Publishing Results.
Louisiana's new ibogaine research law is more careful than Texas's on safety rules, and silent on one thing: whether the public ever gets to see what the trials find.
Ibogaine for Executive Burnout: What's Actually True and What's Marketing
Burnout isn't a medical diagnosis, the WHO says so explicitly. Here's what that means for anyone researching ibogaine for executive burnout, and what the real evidence actually covers instead.
Ibogaine for First Responders: What the Research Actually Supports
Firefighters, police, and EMS workers carry a specific trauma load. Here's what ibogaine research actually covers for this population, and the cardiac risk conversation that matters more here than almost anywhere else.
Is Cheap Ibogaine Treatment Worth the Risk?
Budget ibogaine operations do exist. The problem isn't the price - it's what gets cut to hit it. What corners cost lives.
We Submitted a Public Comment to the FDA on Ibogaine Clinical Trial Safety
We submitted a formal public comment to the FDA on ibogaine clinical trial design and safety, responding to Docket FDA-2026-N-10429. Here is what we told them, and why.
The Texas Ibogaine Initiative: What the $50 Million Bill Actually Funds
Texas signed a $50 million bill funding ibogaine research toward FDA approval. Here's what the money actually covers, and what it does not change for people seeking treatment today.
New Preprint: Ibogaine May Promote Synaptic Plasticity and Neural Repair Through Metabolic Preconditioning
A new preprint suggests ibogaine triggers short-lived metabolic stress in neurons, followed by a rebound in energy production and shifts in pathways linked to synaptic plasticity and repair. The work is still early, uses only cell cultures and mouse tissue, and has not been peer-reviewed.
NDA International vs. University of Miami: The Lawsuit That Split Ibogaine Research
Howard Lotsof and Deborah Mash were ibogaine's two most important early researchers. Then they sued each other over a noribogaine patent, and the field has never fully recovered.
Ibogaine Isn't Only in Iboga: The Other Plants That Contain It
Tabernanthe iboga is not the only plant that produces ibogaine. From the Congo to Madagascar to French Guiana, several little-known species carry the same alkaloid.
How Ibogaine Was Extracted Before It Became a Clinical Product
Before measured capsules and cardiac monitoring, getting usable ibogaine meant real chemistry done informally. The methods explain why purity control became such a persistent problem.
Voacangine and Coronaridine: How They're Connected to Ibogaine
Most ibogaine sold today isn't extracted from iboga root at all. It starts as voacangine. And coronaridine is the molecule behind one of psychiatry's most closely watched experimental addiction drugs.
Microdosing Ibogaine: What the Evidence Actually Shows
Sub-perceptual ibogaine doses are gaining interest for depression and neurological conditions. What the science says so far.
How to Find a Legitimate Ibogaine Clinic: Red Flags and Green Flags
Cardiac screening, licensed physicians, emergency protocols: what separates safe clinics from dangerous ones. A practical vetting checklist.
The Bwiti Tradition: How Iboga Has Been Used for Centuries
Iboga isn't a Western invention. For the Bwiti people of Gabon and Cameroon, it's been a spiritual technology for generations.
Ibogaine Half-Life and Duration: A Timeline of Effects
From ingestion to clearance: how long ibogaine and noribogaine stay active, and what to expect at each phase.
Tabernanthe Iboga: The Plant Behind the Treatment
Ibogaine is extracted from the root bark of Tabernanthe iboga. Here's the botany, the alkaloid profile, and why the whole plant differs from the extract.
Ibogaine Deaths: Causes, Statistics, and How Medical Settings Prevent Them
Between 1990 and 2020, at least 33 deaths were associated with ibogaine. Most were preventable. Here's what the data shows.
Ibogaine vs MDMA-Assisted Therapy: Different Tools for Different Trauma
MDMA therapy (for PTSD) and ibogaine therapy target different problems through different mechanisms. Both have serious evidence.
Ibogaine vs Ketamine Therapy: A Side-by-Side Comparison
Ketamine is FDA-approved and widely available. Ibogaine isn't. But the evidence profiles, mechanisms, and outcomes are very different.
Ibogaine vs Ayahuasca: Key Differences Explained
Both are plant-based psychedelics with therapeutic applications. But the mechanisms, duration, risks, and use cases differ significantly.
The Best Ibogaine Documentaries to Watch
From 'Rite of Passage' to recent VICE and Netflix features — a guide to the best ibogaine documentaries and what each gets right.
Ibogaine Dosage: Flood Dose, Test Dose, and Microdose Explained
Clinics use 10-25mg/kg for flood doses. Test doses come first. Microdoses are different entirely. Here's how each works.
Ibogaine and the Heart: Understanding QT Prolongation Risk
The most serious risk of ibogaine is cardiovascular. Here's exactly what QT prolongation is, who's at risk, and how reputable clinics screen for it.
The Stanford Ibogaine Study: What the Veterans Research Found
Stanford researchers followed veterans with TBI, PTSD, and depression through ibogaine treatment in Mexico. The results were striking.
Noribogaine: What Ibogaine's Active Metabolite Does in Your Body
Ibogaine converts to noribogaine in the liver. This metabolite stays active for weeks — and may be responsible for the lasting effects.
GDNF and Ibogaine: The 'Brain Fertilizer' Theory
Ibogaine increases glial cell line-derived neurotrophic factor. Here's what that means for addiction recovery and neuroplasticity.
Ibogaine vs Psilocybin: Which Works Better for Addiction?
Psilocybin gets more clinical press. Ibogaine has more addiction-specific data. A direct comparison of what each does.
How Ibogaine Was Discovered by Western Science
Ibogaine went from French colonial curiosity in the 1860s to scheduled substance in 1970 to serious addiction research in the 1980s. The full timeline.
Lambarène: The Over-the-Counter Ibogaine Stimulant Named After Albert Schweitzer's Hospital
From 1939 to 1966, French pharmacies sold ibogaine as a stimulant called Lambarène, named after the Gabon hospital town where Albert Schweitzer spent his career. Here's the real story behind the name, the doping ban, and how a heroin user's accidental discovery in 1962 redirected the compound's history entirely.
The Ibogaine Afterglow Period: What to Expect in the Weeks After
Most people report an extended period of clarity, reduced cravings, and emotional openness after ibogaine. Here's what drives it and how long it lasts.
What Does an Ibogaine Experience Actually Feel Like?
From the first hour to the afterglow days later. First-person accounts, clinical descriptions, and what most people get wrong about the ibogaine experience.
How Much Does Ibogaine Treatment Cost? A 2026 Breakdown
Ibogaine treatment ranges from $3,000 to $25,000+ depending on location, program length, and clinic quality. Here's what drives the price.
Joe Rogan and Ibogaine: What He Said and Why It Matters
Joe Rogan has discussed ibogaine on multiple episodes of his podcast. His reach made it a household topic. Here's exactly what he said and the context.
How Ibogaine Resets the Brain: The Neuroscience Explained
What actually happens in your nervous system during and after ibogaine treatment. BDNF, NMDA receptors, and why the reset lasts.