Blog & Research

Evidence-based guides, research summaries and patient perspectives

Ibogaine Informed Consent: What Should Be Disclosed

What to ask before consenting to ibogaine: evidence, risks, alternatives, research status, medical responsibility, costs, privacy, and declining treatment.

Editorial Team7 min read

How to Talk to Your Doctor About Ibogaine

Prepare for a medical conversation about ibogaine: treatment goals, records, medication questions, evidence, alternatives and follow-up care.

Editorial Team6 min read

Repeat Ibogaine Treatment and Booster Doses: Evidence and Risks

What research does and does not show about repeat ibogaine treatment and booster doses, including cardiac risks and questions for providers.

Editorial Team6 min read

How to Evaluate Ibogaine Research and Clinical Studies

A framework for reading ibogaine research: study design, who was studied, denominators behind percentages, and why registration isn't a result.

Editorial Team6 min read

Ibogaine and Antidepressants: Why Medication Review Matters

Understand the evidence on ibogaine and antidepressants: CYP2D6, QT effects, serotonergic concerns and why stopping medication needs clinical oversight.

Editorial Team5 min read

Ibogaine and the Risk of Mania or Psychosis: Evidence and Warning Signs

What case reports show about mania and psychosis after ibogaine, what remains unknown, and which changes call for psychiatric or emergency assessment.

Editorial Team6 min read

Ibogaine and Benzodiazepines: Dependence, Withdrawal, and Safety Risks

What ibogaine research does not establish about benzodiazepine withdrawal, why abrupt stopping can be dangerous, and what to discuss with a clinician.

Editorial Team6 min read

Does a Normal ECG Make Ibogaine Safe?

A normal ECG cannot guarantee ibogaine safety. Learn what baseline QTc shows, why drug effects change the picture and what to ask about monitoring.

Editorial Team5 min read

Ibogaine's Neurological and Psychological Effects: What Is Known

Separate ibogaine's acute perceptual effects, ataxia, cognitive findings and psychiatric concerns, with clear limits on what research can establish.

Editorial Team6 min read

Federico Fiuzzi's 2011 Ibogaine Death in Slovenia: New Details from Court Records

Ibogaine Club contacted the District Court in Maribor about Federico Fiuzzi's 2011 ibogaine death. The court confirmed a 2013 investigation request was withdrawn and criminal proceedings never opened.

Editorial Team5 min read

Gabon and Ambio Life Sciences Discuss Iboga Partnership. What Will It Mean for Local Communities?

Gabon and Ambio Life Sciences are exploring a partnership around iboga. But will local communities, researchers, and traditional knowledge holders have a meaningful role in the industry’s future, or will most of the value continue to flow abroad?

Editorial Team4 min read

Ibogaine Success Rates: What Published Studies Actually Measure

There is no single reliable ibogaine success rate. Here's what withdrawal relief, abstinence, and follow-up numbers in the published research actually measure, and what they don't.

Editorial Team9 min read

Iboga vs Ibogaine: The Plant Is Not the Same as the Dose

Iboga is the plant. Ibogaine is one alkaloid inside it, at a concentration nobody can estimate by looking.

Editorial Team7 min read

Buying Raw Iboga Root Bark Online: What You Are Actually Getting

A gram of iboga root bark from one seller is not the same dose as a gram from another. Lab data shows why that gap can be fatal.

Editorial Team8 min read

Where Iboga Came From: 26 Versions of One Myth

A woman reaches into a river hole chasing a catfish and pulls out her dead husband's bones instead. What happens next became the founding myth of Fang Bwiti, told in at least 26 documented versions that disagree with each other on almost everything except what matters most.

Editorial Team11 min read

Who Is NOT a Candidate for Ibogaine Treatment?

Cardiac conditions, certain medications, liver disease, psychiatric history - the absolute and relative contraindications, explained without jargon.

Editorial Team6 min read

Iboga Never Works Alone: The Plants That Surround Every Bwiti Ceremony

Palm wine fortified with bitter bark, kola nuts passed hand to hand, cannabis some branches call a fourth sacrament, and a second visionary plant Western botanists misidentified for nearly a century. Iboga never worked in isolation.

Editorial Team10 min read

Discovering Bwiti: The First Written Record of a Ceremony, 1865

In 1865 an explorer sat through a Bwiti ceremony he found tedious and wrote it down anyway. That bored, half-honest account is the oldest surviving eyewitness record of the tradition, and it reveals how much of the early written history of Bwiti has been silently rewritten in translation.

Editorial Team11 min read

The Persecution of Bwiti: Gabon and Equatorial Guinea, 1930-1950

For two decades, missionaries and colonial administrators in Gabon and Spanish Guinea ran a coordinated campaign to destroy Bwiti, using raids, torture, and executions justified by a cannibalism myth nobody could ever actually prove. This is the documented history, with names, dates, and court records.

Editorial Team11 min read

Ibogaine Aftercare & Integration: The 30, 60 and 90 Days After Treatment

The session opens a window. What you do in the weeks and months after determines whether the changes last.

Editorial Team6 min read

Gabon Moves to Restrict Iboga Exports While Building a Domestic Framework

Gabon is tightening controls on iboga, with a May 2026 decree regulating its use and traditional knowledge and a September draft decree proposing a full export ban on the plant and all its derivatives.

Editorial Team3 min read

Tabernanthalog (TBG) vs. Ibogaine: What the Research Shows So Far

Tabernanthalog (TBG, DLX-007) is a synthetic ibogaine analog designed to keep the therapeutic signal and drop the hallucinogenic ordeal and cardiac risk. Here's the real receptor data, what the animal studies show, where Delix Therapeutics' clinical program actually stands in 2026, and how TBG stacks up against ibogaine itself.

Editorial Team11 min read

Louisiana Is Funding Ibogaine Trials With Opioid Settlement Money. The Law Doesn't Require Publishing Results.

Louisiana's new ibogaine research law is more careful than Texas's on safety rules, and silent on one thing: whether the public ever gets to see what the trials find.

Editorial Team8 min read

Ibogaine for Executive Burnout: What's Actually True and What's Marketing

Burnout isn't a medical diagnosis, the WHO says so explicitly. Here's what that means for anyone researching ibogaine for executive burnout, and what the real evidence actually covers instead.

Editorial Team5 min read

Ibogaine for First Responders: What the Research Actually Supports

Firefighters, police, and EMS workers carry a specific trauma load. Here's what ibogaine research actually covers for this population, and the cardiac risk conversation that matters more here than almost anywhere else.

Editorial Team5 min read

Is Cheap Ibogaine Treatment Worth the Risk?

Budget ibogaine operations do exist. The problem isn't the price - it's what gets cut to hit it. What corners cost lives.

Editorial Team5 min read

We Submitted a Public Comment to the FDA on Ibogaine Clinical Trial Safety

We submitted a formal public comment to the FDA on ibogaine clinical trial design and safety, responding to Docket FDA-2026-N-10429. Here is what we told them, and why.

Editorial Team7 min read

The Texas Ibogaine Initiative: What the $50 Million Bill Actually Funds

Texas signed a $50 million bill funding ibogaine research toward FDA approval. Here's what the money actually covers, and what it does not change for people seeking treatment today.

Editorial Team6 min read

New Preprint: Ibogaine May Promote Synaptic Plasticity and Neural Repair Through Metabolic Preconditioning

A new preprint suggests ibogaine triggers short-lived metabolic stress in neurons, followed by a rebound in energy production and shifts in pathways linked to synaptic plasticity and repair. The work is still early, uses only cell cultures and mouse tissue, and has not been peer-reviewed.

Editorial Team3 min read

NDA International vs. University of Miami: The Lawsuit That Split Ibogaine Research

Howard Lotsof and Deborah Mash were ibogaine's two most important early researchers. Then they sued each other over a noribogaine patent, and the field has never fully recovered.

Editorial Team5 min read

Ibogaine Isn't Only in Iboga: The Other Plants That Contain It

Tabernanthe iboga is not the only plant that produces ibogaine. From the Congo to Madagascar to French Guiana, several little-known species carry the same alkaloid.

Editorial Team6 min read

How Ibogaine Was Extracted Before It Became a Clinical Product

Before measured capsules and cardiac monitoring, getting usable ibogaine meant real chemistry done informally. The methods explain why purity control became such a persistent problem.

Editorial Team5 min read

Voacangine and Coronaridine: How They're Connected to Ibogaine

Most ibogaine sold today isn't extracted from iboga root at all. It starts as voacangine. And coronaridine is the molecule behind one of psychiatry's most closely watched experimental addiction drugs.

Editorial Team7 min read

Microdosing Ibogaine: What the Evidence Actually Shows

Sub-perceptual ibogaine doses are gaining interest for depression and neurological conditions. What the science says so far.

Editorial Team5 min read

How to Find a Legitimate Ibogaine Clinic: Red Flags and Green Flags

Cardiac screening, licensed physicians, emergency protocols: what separates safe clinics from dangerous ones. A practical vetting checklist.

Editorial Team11 min read

The Bwiti Tradition: How Iboga Has Been Used for Centuries

Iboga isn't a Western invention. For the Bwiti people of Gabon and Cameroon, it's been a spiritual technology for generations.

Editorial Team10 min read

Ibogaine Half-Life and Duration: A Timeline of Effects

From ingestion to clearance: how long ibogaine and noribogaine stay active, and what to expect at each phase.

Dr. Mara Ellison7 min read

Tabernanthe Iboga: The Plant Behind the Treatment

Ibogaine is extracted from the root bark of Tabernanthe iboga. Here's the botany, the alkaloid profile, and why the whole plant differs from the extract.

Editorial Team5 min read

Ibogaine Deaths: Causes, Statistics, and How Medical Settings Prevent Them

Between 1990 and 2020, at least 33 deaths were associated with ibogaine. Most were preventable. Here's what the data shows.

Editorial Team11 min read

Ibogaine vs MDMA-Assisted Therapy: Different Tools for Different Trauma

MDMA therapy (for PTSD) and ibogaine therapy target different problems through different mechanisms. Both have serious evidence.

Editorial Team5 min read

Ibogaine vs Ketamine Therapy: A Side-by-Side Comparison

Ketamine is FDA-approved and widely available. Ibogaine isn't. But the evidence profiles, mechanisms, and outcomes are very different.

Editorial Team5 min read

Ibogaine vs Ayahuasca: Key Differences Explained

Both are plant-based psychedelics with therapeutic applications. But the mechanisms, duration, risks, and use cases differ significantly.

Editorial Team6 min read

The Best Ibogaine Documentaries to Watch

From 'Rite of Passage' to recent VICE and Netflix features — a guide to the best ibogaine documentaries and what each gets right.

Editorial Team8 min read

Ibogaine Dosage: Flood Dose, Test Dose, and Microdose Explained

Clinics use 10-25mg/kg for flood doses. Test doses come first. Microdoses are different entirely. Here's how each works.

Editorial Team6 min read

Ibogaine and the Heart: Understanding QT Prolongation Risk

The most serious risk of ibogaine is cardiovascular. Here's exactly what QT prolongation is, who's at risk, and how reputable clinics screen for it.

Editorial Team5 min read

The Stanford Ibogaine Study: What the Veterans Research Found

Stanford researchers followed veterans with TBI, PTSD, and depression through ibogaine treatment in Mexico. The results were striking.

Editorial Team5 min read

Noribogaine: What Ibogaine's Active Metabolite Does in Your Body

Ibogaine converts to noribogaine in the liver. This metabolite stays active for weeks — and may be responsible for the lasting effects.

Editorial Team5 min read

GDNF and Ibogaine: The 'Brain Fertilizer' Theory

Ibogaine increases glial cell line-derived neurotrophic factor. Here's what that means for addiction recovery and neuroplasticity.

Editorial Team5 min read

Ibogaine vs Psilocybin: Which Works Better for Addiction?

Psilocybin gets more clinical press. Ibogaine has more addiction-specific data. A direct comparison of what each does.

Editorial Team6 min read

How Ibogaine Was Discovered by Western Science

Ibogaine went from French colonial curiosity in the 1860s to scheduled substance in 1970 to serious addiction research in the 1980s. The full timeline.

Editorial Team6 min read

Lambarène: The Over-the-Counter Ibogaine Stimulant Named After Albert Schweitzer's Hospital

From 1939 to 1966, French pharmacies sold ibogaine as a stimulant called Lambarène, named after the Gabon hospital town where Albert Schweitzer spent his career. Here's the real story behind the name, the doping ban, and how a heroin user's accidental discovery in 1962 redirected the compound's history entirely.

Editorial Team6 min read

The Ibogaine Afterglow Period: What to Expect in the Weeks After

Most people report an extended period of clarity, reduced cravings, and emotional openness after ibogaine. Here's what drives it and how long it lasts.

Editorial Team6 min read

What Does an Ibogaine Experience Actually Feel Like?

From the first hour to the afterglow days later. First-person accounts, clinical descriptions, and what most people get wrong about the ibogaine experience.

Editorial Team5 min read

How Much Does Ibogaine Treatment Cost? A 2026 Breakdown

Ibogaine treatment ranges from $3,000 to $25,000+ depending on location, program length, and clinic quality. Here's what drives the price.

Editorial Team6 min read

Joe Rogan and Ibogaine: What He Said and Why It Matters

Joe Rogan has discussed ibogaine on multiple episodes of his podcast. His reach made it a household topic. Here's exactly what he said and the context.

Editorial Team5 min read

How Ibogaine Resets the Brain: The Neuroscience Explained

What actually happens in your nervous system during and after ibogaine treatment. BDNF, NMDA receptors, and why the reset lasts.

Editorial Team5 min read