Ibogaine Clinical Trials
A live directory pulled directly from ClinicalTrials.gov, the U.S. National Library of Medicine's public registry. Tracking 10 studies, 2 currently recruiting.
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Most Significant Trials
Recruiting
Mapping Ibogaine Neural Dynamics in Opioid Use Disorder
University of California, Irvine · United States
Opioid Use Disorder (OUD)
One of the few actively recruiting US academic ibogaine trials, focused on neural mechanisms in opioid use disorder rather than just outcomes. This kind of mechanistic data is what regulators and future trial designers draw on.
NCT07226570 · View on ClinicalTrials.gov →
Active, Not Recruiting
Pre-post Evaluation of the Safety and Efficacy of Ibogaine-Magnesium Therapy in Veterans With Repeated Blast Exposure
Stanford University · United States
Blast or Combat ExposureHead Injury Trauma
Stanford's ibogaine-magnesium protocol for veterans with repeated blast exposure (TBI) is the closest thing to a controlled academic study behind the widely cited veteran outcome data. Magnesium co-administration is specifically aimed at reducing the cardiac QTc burden.
NCT04313712 · View on ClinicalTrials.gov →
CompletedPhase 2
Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification
International Center for Ethnobotanical Education, Research, and Service · Spain
Drug DependenceDrug Use DisordersOpioid Dependence
ICEERS (Barcelona) ran one of the first prospective safety and efficacy studies on ibogaine specifically for methadone detoxification, directly relevant to anyone considering ibogaine to come off long-term opioid maintenance therapy.
NCT04003948 · View on ClinicalTrials.gov →
CompletedPhase 1/Phase 2
A Study of Oral Ibogaine in Opioid Withdrawal
atai Therapeutics, Inc. · United Kingdom
Opiate Withdrawal Syndrome
atai Therapeutics' oral ibogaine study for opioid withdrawal represents pharmaceutical industry investment in a standardized, reproducible ibogaine dosing protocol rather than the variable protocols used at most retreat-style centers.
NCT05029401 · View on ClinicalTrials.gov →
CompletedPhase 2
Ibogaine in the Treatment of Alcoholism: an Open-label Escalating-dose Trial
University of Sao Paulo · Brazil
Alcoholism
One of the earliest formal open-label dose-escalation studies on ibogaine for alcoholism, conducted in Brazil where ibogaine sits in a more established medical research tradition than in the US.
NCT03380728 · View on ClinicalTrials.gov →
All Other Trials (5)
Active, Not Recruiting
Trifecta Research Study
Axial Therapeutic Research · United States
PTSD - Post Traumatic Stress DisorderCognitive DysfunctionBrain Injury
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (…
NCT07717866 · View on ClinicalTrials.gov →
Not Yet RecruitingPhase 1/Phase 2
Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder
Clive Michelsen · United States
Opioid Use DisorderOpioid WithdrawalSubstance Use Disorders
IBO-CARE is a single-site Phase 1/2a study evaluating the safety, tolerability, feasibility and preliminary outcomes of medically supervised ibogaine …
NCT07871877 · View on ClinicalTrials.gov →
Status Unknown
Personality and Drug Use
Psychedelic Data Society
No Conditions Study Focus on Substance Use and Personality
This is an observational, naturalistic study that aims to assess whether people with different histories of recreational or therapeutic illicit substa…
NCT05516823 · View on ClinicalTrials.gov →
WithdrawnPhase 2
Trifecta Research Study
Johns Hopkins University · United States
PTSD - Post Traumatic Stress DisorderCognitive DysfunctionBrain Trauma
The Special Operations Care-Fund (SOC-F) will sponsor the application of four treatments - hormone replacement, magnetic resonance brain stimulation, …
NCT06810765 · View on ClinicalTrials.gov →
Withdrawn
Personality and Drug Use (PDU)
Quantified Citizen Technologies Inc.
Personality
The study aims to assess whether the use of drugs relates to personality ratings. Specifically, we plan to investigate if people with different histor…
NCT05180149 · View on ClinicalTrials.gov →
Data sourced live from the U.S. National Library of Medicine's ClinicalTrials.gov registry and refreshed daily, matching any study that mentions ibogaine. Some of these are multi-compound protocols (for example, ibogaine combined with 5-MeO-DMT or magnesium therapy) rather than ibogaine-only trials. Read each summary to see exactly how ibogaine fits into that study's design. Listing a trial here is not an endorsement, and Ibogaine.club is not affiliated with any of these studies. This is educational information, not medical advice. Ibogaine is investigational in the United States and not FDA-approved.