A 40-year-old man died in the United Kingdom in 2000 after taking an iboga alkaloid extract during opioid detoxification.
The series reports vomiting shortly before death and underlying liver fibrosis associated with hepatitis C. The autopsy attributed the death to a fatal reaction to the preparation. Also covered by Corkery (2018) as the first UK case; same person as Alper case 4 (do not duplicate).
Sources:
- Alper, K. R., Stajić, M. & Gill, J. R. Fatalities Temporally Associated with the Ingestion of Ibogaine. J. Forensic Sci. 57, 398-412 (2012). Table 1, case 4. https://doi.org/10.1111/j.1556-4029.2011.02008.x
- ICEERS literature compilation, row 4. https://www.iceers.org/wp-content/uploads/2026/02/ICEERS2012_Ibogaine_literature_compilation.pdf
- Corkery, J. M. Ibogaine as a Treatment for Substance Misuse. Prog. Brain Res. 242, 217-257 (2018). https://pubmed.ncbi.nlm.nih.gov/30471681/
Investigation & Causality
Substance Reported
Tabernanthe iboga alkaloid extract
Exposure Context
Medical clinic
Ibogaine Causality
Alleged
Case Reference
Alper et al. 2012, Table 1, case 4
Case Details
Location
United Kingdom
Age
40
Sex
Male
Cause of Death (as first reported)
Fatal reaction to the iboga preparation, per reported autopsy