Ibogaine Research Database

[Aminergic correlations in the rat brain exposed to hypobaric hypoxia].

The action of tabernanthine on noradrenaline-stimulated contractions and 45Ca movements in rat isolated vascular smooth muscle.

The iboga alkaloid tabernanthine inhibited depolarization (100 mM K+)-induced contractions in aorta and mesenteric arteries in an concentration-dependent manner with the respective IC50 values being about 21 and 7 microM. Contractions elicited by noradrenaline in the mesenteric a...

Cholecystokinin octapeptide (CCK-8), ceruletide and analogues of ceruletide: effects on tremors induced by oxotremorine, harmine and ibogaine. A comparison with prolyl-leucylglycine amide (M

Cholecystokinin octapeptide (CCK-8), ceruletide (caerulein, CER) and 10 analogues of ceruletide, were studied in mice for antagonism of the tremors induced by harmine (5 mg/kg, s.c.), ibogaine (20 mg/kg, s.c.) and oxotremorine (0.2 mg/kg, s.c.). The following reference drugs were...

[Religion of Eboga or the Bwiti of the Fangs].

[Effects of tabernanthine on various cardiovascular parameters in the rat and dog (author's transl)].

1. Tabernanthine produced, in anaesthetized Rat and Dog, bradycardia and hypotension which remained after atropine or vagotomy. Bradycardia was significant from 0,5-0,8 mg . kg-1. The degree of hypotension depended upon the anaesthetic. 2. Effects of tabernanthine on cardiovascul...

[Restoration of sleep in cats pretreated with tabernanthine p-chlorophenoxyacetate (SAD 103) (author's transl)].

The effects upon sleep returning after an effective dose of Tabernanthine p-chlorophenoxyacetate (SAD 103) are studied on chronically implanted cats. The near-total insomnia lasting for 6-8 h provoked by SAD is characterized by a calm waking period broken by periods of drowsiness...

[Modification of awake-sleep equilibrium by tabernanthine and some of its derivatives in the cat (author's transl)].

Intraperitoneal injections (ip.) of 4 alkaloid derivatives of ibogamine: tabernanthine tartrate (2 mg/kg), methoxy-16 ibogaine tartrate (SAD 121 - 3 mg/kg), methoxy-16 tabernanthine tartrate (SAD 122 - 2 mg/kg), and tabernanthine parachlorophenoxyacetate (SAD 103 - 7 mg/kg), were...

Effect of tabernanthine on the turnover time of brain catecholamines in normal and hypobaric hypoxic rats.

The central effects of tabernanthine on noradrenaline and dopamine turnover times were studied in the hypothalamus, the striatum and the remainder of the brain of normal and hypobaric hypoxic rats, the latter state corresponding to 5,200m (410mm Hg) and 7,000m (320mm Hg). Catecho...

Hormonal profile of coronaridine hydrochloride--an antifertility agent of plant origin.

[The effect of alkaloids from Tabernanthe iboga H. Bn. on the response of isolated organs to catecholamines and the possible role of calcium exchange. Case of Ibogaine].

On isolated Rat duodenum, ibogaine (70 mumoles/l) increases the hypertonic effect following the addition of Calcium ions to the organ previously decalcified. Moreover, this alkaloid increases the hypotomic effect resulting from decalcification of the normal organs. These actions ...

[Transformation of the Iboga alkaloid voacangine into voaketone, a derivative of beta-carboline (author's transl)].

13C-NMR. Spectroscopy of naturally occurring substances. XLV. Iboga alkaloids.

[Detection of ibogaine in organic liquids].

[Indole alkaloids induction of tremors: effect on photosensible epilepsy in Papiopapio].

Harmaline and ibogaine i.v. administration induced in the photosensitive baboon restlesness and tremor (8-12 Hz). The former increased the EEG frequency particularly in central regions with appearance of bursts at 20-24 c/s and blocked by somatic movement. The latter produced a s...

Gas chromatographic determination of ibogaine in biological fluids.

The identification of ibogaine in biological material.

Methods for the detection and determination of ibogaine in biological materials.

ALKALOIDS OF VOACANGA SCHWEINFURTHII STAPF: VOACORINE AND VOACANGINE.

[ALKALOIDS OF THE TABERNAEMONTANA PANDACAQUI POIR. ISOLATION OF CORONARIDINE].

Tumor inhibitors. II. Alkaloids of Ervatamia dichotoma. Isolation, crystallization, and pharmacological properties of coronaridine.

[The conversion of voacorine into voacristine by acid splitting].

[Voacanga alkaloids. V. Relationship of vobasine to dregamine and tabernaemontanine].

[Voacanga alkaloids. IV. Structure of voacryptin and voacristine].

[On voacangine, alkaloid from Voacanga africana-Staff-Apocynaceae].

Alkaloids of Voacanga schweinfurthii Stapf. I. Voacamine and vobtusine.

[Apropos of the reinforcing and bradycardiac effects of the strophanthin-voacamine combination].

[Voacanga alkaloids. III. Voacristine: identity with voacangarine and decomposition to iboxygaine and ibogaine].

[Paralyzing effects of voacamine sulfate on the hypothalamic centers].

[Pharmacodynamics in comparing voacamine & voacorine, alkaloids from Voacanga africana Stapi (Apocynaceae)].

[Pharmacodynamic study of voacamine, an alkaloid of Voacanca africana, Apocynaceae].

[Drugs increasing cardiotonic effects of vóacamine & voacaline].

Neuropharmacological studies on ibogaine, an indole alkaloid with central-stimulant properties.

Effects of LSD 25, BOL 148, bufotenine, mescaline and ibogaine on the potentiation of hexobarbital hypnosis produced by serotonin and reserpine.

Analysis of the cardiovascular action of ibogaine hydrochloride.

[Effect of voacamine sulfate on the fatigued heart].

[Analgesic properties of voacamine].

[Effects of voacamine sulfate on blood coagulation].

[Voacamine sulfate, a new major cardiotonic].

[Voacamine camphosulfonate].

Potentiation action of ibogaine (bogadin TM) on morphine analgesia.

[Enhancement of the cardiotonic effects of voacamine sulfate in the presence of aminophylline and heptaminol hydrochloride].

[Of the physiological action of iboga, Tabernanthe iboga H. Bn., And of ibogaine; effect on muscle chronaxis].