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patientorchard
21 Sept 2026

Iboga and Nootropics ~ Contraindication or Synergy?

Based on these particular Nootropics but I ask in general if a microdose or post flood Iboga experience will work with a Nootropic program. http://www.newstarnootropics.com/ If anyone knows or has experience combining these please let me know. I know we have this thread... http://Ibogaine.club/index.php?topic=833.0 But no talk about if Nootropics and Iboga get along.  Once again JBG?  Go to guy when in the clutch.
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gentlebeaver30· 21 Sept 2026

i tried some nootropics a few years back and got headaches so...... i stick to nature's nootropics gingko ashwaganda gota kola brahmi they go well pre and post flood (always stopped 2 days before and started 2 days after flood) and work well with microdosing significantly increases focus, memory, awareness. and 'control' also Golden Root (Rhodiola rosea ) Maral root (Rhaponticum carthamoides) Ginseng Foti

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gentlebeaver30· 30 Sept 2026

Time to bring this thread back to life for everyone's benefit I always try to stay open and willing to try new things Back in  the day we had a saying "better living thru chemistry" so i thank the russians for the research and Nexus for the thread https://www.dmt-nexus.me/forum/default.aspx?g=posts&t=38876 "Noopept massively potentiates iboga" NOOPEPT is simply one of the greatest discoveries I have ever added to my daily life. I realize that 10 days is early on to make such a zealous statement but this wonder whirl is legal, safe and actually quite healthy and beneficial to the brain (neuroplasticity, neuroprotective, etc) Even after all the years of diet, nutrition, herbs, meditation, microdosing - it was like someone just finally plugged my brain in or hit the on button hard to describe it more than that it is not like an amphetamine or coffee or microdosing it is just ...... more..... on more energy, more focus, more aware, etc etc sleep and even naps are not a problem waking up more awake google search for all of the scientific info, experiental stories, faqs etc after 10 days - yesterday started the real adventure NOOPEPT + IBOGA my initail goal was to see if the potentiation of root bark would allow for lower doses thus bypassing the toxicity issue which limits the length of the cycle of the microdosing so day 1 100 mg of root bark + Noopept - which I have found that 30 mg am and 20 mg pm is ideal for now (the Russians advise 10 - 30 mg 1-3x / day, with a one month break after each 3 months) It seems that the affect of the dosage changes proportionately 10 mg is nice, 20 is more, but for me 30 turns the house lights on ! little affect from the rootbark but no contraindications felt day 2 a.m.: 400 mg of r.b. + 30 mg noopept p.m.: 400 mg r.b + 20 mg noopept this is going to be fun !!!! my wild side wants to quickly up the dosage but i will go slow it is as if the noopept hit the on switch, and the rootbark is functioning like a microscope / telescope or maybe i could call it "iboga photoshop" noopept certainly ups the brightness and clarity while iboga is adding ... dimensionality jbg

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jojo· 21 Sept 2026

Hey Kambo. I love nootropics when they work for me. I usually combine psychedelics with piracetam, pramiracetam, or aniracetam. The thing for me is getting the dose right. Most people seem to take a lot of piracetam. I find that 250 mg works great for me. I feel a bood boost in creativity and music appreciation. Sometimes if I dose higher I will get negative effects from it. Aniracetam has my favorite effects but it has a sort of comedown with me. This might be because I need to supplement with more choline towards the end of it though. All of my senses are heightened and sharper. I think, at least for my self, that nootropics need to be cycled. I find if I dose days in a row I feel only negative effects. This is especially true with hydergine, another cool nootropic. I think most nootropics boost BDNF in the brain so I think that they could be used synergistically with Iboga's GDNF increasing properties. I would love to discuss this further.

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rosyfern67· 21 Sept 2026

Thanks for the information ppl, I was going to start a thread on contraindications. Im micro dosing at the moment but I wanted to take asgawandha at the same time and was concerned if it might be too much at the same time. Are there any issues regarding taking the two? Also I have in my posession some tho rhodiola, brahmi, gout kola. I believe you have answeRed my question already but wanted to know if I should be wary of any problems.

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gentlebeaver30· 21 Sept 2026

go slow start low and listen to your body

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patientorchard· 30 Sept 2026

^ Ringing endorsement from someone I view as a true teacher.  So I guess I shall try.  Which particular Nootropic is it that you are using?  I see there are many.

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gentlebeaver30· 30 Sept 2026

my advice is to try a tiny amount to see if you resonate with it NOOPEPT - as powder or pill remember the doasge is between 10 - 50 mg a day only so buy a SMALL amount as some people report no effect than if you like it i will hook you up with my chinese friends who are reliable, good quality and comes out to pennies a day

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berry36· 30 Sept 2026

wow. . ! i love you boys you are really something  <3 btw webmaster, where is the heart . . ?

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gentlebeaver30· 02 Oct 2026

before i post how amazing the week trial of noopept + root bark was i want to first clarify one important question DOES IBOGAINE INCREASE GLUTAMATE IN THE BRAIN ? IF SO - NOOPEPT + IBOGAINE MIGHT INCREASE EXCITOTOXICITY AMPA is a glutamate receptor partly responsible for excitation of neurons. Racetams (noopept) increase the action AMPA receptors, so when something binds to them, they have a greater response. Adderall (DOES IBOGAINE ?) increases available glutamate. On the one hand, you've give neurons the ability to become excited more easily, and then you increase the amount of chemical available that excites the neurons. This creates a synergy. Excitotoxicity occurs when a neuron becomes too excited, it fires too much, and is damaged because of it. The postulate here is that this synergistic effect could increase the excitation of neurons to the point where they are damaged. UPDATED ONE HOUR LATER It could be that the reported "massive potentiation" is actually excitotoxicity as many reports specifically indicate ibogaine and its possibly causing increased glutamate in the brain even more is the following study Neuroreport. 1995 Aug 21;6(12):1611-6. Excitotoxic insult due to ibogaine leads to delayed induction of neuronal NOS in Purkinje cells. O'Hearn E, Zhang P, Molliver ME.

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patientorchard· 02 Oct 2026

Are you saying it doesn't sound like a good idea?  Preliminary at least, looks not good?  I haven't been inclined to venture in this way as of yet.  The person I asked for had extremely great results and said it "fixed or cured" their memory issues.  Sorry I had to ask to make sure as sometimes scientific terms cause confusion in me.  Are you going to discontinue use then?  Thanks

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gentlebeaver30· 02 Oct 2026

i just spoke with a very pro-psychotropic scientist who was involved in the govt's toxicity research on ibogaine research in the 90's. What he / she remembers is that the reasons why ibogaine was not approved for further govt research was the data showing that ibogaine alone appeared to be causing excitotoxicity in monkeys. With that in mind, and with the limited understanding i have of ibogaine / glutamate, and with the POSSIBLE increased potentiality for excitotoxicity when combining ibogaine with any racepam - i am going to take a break from microdosing the root bark until i have further information - and continue with the noopept. My decision is based on: 1. the fact that i have been microdosing root bark in cycles for almost 3 years already 2. the fact that noopept is wonderous and has lots of potential to explore (memory, focus, awareness, joining right left hemisheres, etc etc) 3. the toxicity i have always felt while microdosing which always limited me to 3 week cycles (ironically i always believed the toxicity was in liver - it now appears their is {also} neural toxicity) 4. the potential of increasing toxicity by combining the 2 I am happy that the possibility of potentiating ibogaine with noopept led me to the discovery of noopept, and an increased medical knwledge of root bark i would like to summarize that I DO NOT ADVISE TAKING EITHER BOOSTER OR FLOOD DOSES OF IBOGA / IBOGAINE WHILE USING NOOPEPT OR ANY OTHER RACEPAM interesting, back when i was doing quite a bit of flooding and boosters during a period of time when i was taking daily doses of brahmi and other natural nootrpics, i always felt that it was unsafe to take the brahmi during the flood ( or booster) or immediately before or after.

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patientorchard· 02 Oct 2026

Based on this, I will remain satisfied with mainly Singado (Nicotiana Rustica drinking through nose), Rape' snuff (Nicotiana Rustica mixed with various herbs made by indigenous Pano family tribes) and natural herbs like Blue Green Algae.  Not worth the risk.  I especially find the Singado is so nice with micro dosing.  That would also explain why I can never go too long microdosing.  Thanks for all the valuable information.

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earnestdeer· 04 Oct 2026

Thanks JBG for the detailed info.  I just received my 10grams of Noopept from Cerebral Health.  It seems that most reports are people experiencing noticeable effects after 10-14 days.  I going to prepare them now and start tomorrow.  Not sure on dosage yet.  I will have stopped my last 3 week bark MDing schedule about 3 weeks ago.  I will make sure to not MD for the next 2 weeks at least while I experiment with this.  Very excited.  The stuff wasn't cheap.  But I cannot keep drinking these 5 hour energies to focus/motivate.

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gentlebeaver30· 04 Oct 2026

1. I trust the russians who invented it. they are very clear in their instructions 10 - 30 mg repeated 1-3x /day; ideally 60 mg max per day i started with 10 mg, then tried 20, then 30 i found for me  30 first thing in morning, 20 midday, and once in a while 10 in the late afternnon the russians are also very clear that it must be cycled max of 3 months on, then 1 month off 2. i found and felt the effects immediate on first dose so did all the people i turned on however, there was a huge shift in its affects after 2 1/2 weeks for me some people say it tapers down i found it kicked into a higher gear 3. i found studies showing that ibogaine prevents and protects from excitotoxicity 4. please note: ibogaine is an nmda antagonist and noopept is an nmda agonist enjoy

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earnestdeer· 04 Oct 2026

Thanks JBG.  Would you please clarify the above statements?  It sounds like you are saying you are still weary about MDing and taking Noopept together....? Forgive me for 'glutamate receptors' are not my best understood neuro-function.      I aced cognitive neuroscience and I am still trying to decipher your message here.  I was thinking of doing seasonal MDing before I read these concerns and before I even heard of Noopept, but if Noopept works as well as I hope, then cycling that may be enough.  What a world!

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gentlebeaver30· 04 Oct 2026

It sounds like you are saying you are still weary about MDing and taking Noopept together....?    I aced cognitive neuroscience and I am still trying to decipher your message here.  I was thinking of doing seasonal MDing before I read these concerns and before I even heard of Noopept, but if Noopept works as well as I hope, then cycling that may be enough.  What a world! 3. The worry I had would be that iboga + noopept might cause excitotoxicity It now seems that this might NOT be the case 4. I have no idea what this means. It could mean they cancel each other out. However this is NOT what i experienced - although there were 'aspects' of this If we would say that ibogaine was only an nmda antagonist and noopept was only an nmda agonist then it would be simple; but each one affects the brain and neuro systems in so many ways MOST of which are not understood yet I plan on another 3 round cycle in a  few weeks In actuality theh safest way might be 3 months noopept followed by 1 month root bark, etc

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earnestdeer· 04 Oct 2026

3 months Noopept, 1 month RB, hmmm First off, I am flabbergasted at the effects of today ALONE.  Mind you I was unable to measure with accuracy, but I'd like to think I dosed 3 times today with Noopept from (CH) approx. 30-60mgs total.  I will get more accurate soon.  Stupid scale is cheap.  Now, I smoke weed, you could consider me a connoisseur.  I am medically approved to do so, and I love it.  It certainly has it's demotivating effects (and I will cut back soon, I can feel it), but I think for the purpose of this experiment, I must continue to do so for at least the first two stages of reported noticed effects.  For example, I smoked some green flower today per usual, did my doses of Noopept, and felt effects that had no chance of being placebo.  I was smoking ganja and got laser sharp focus and was reading and writing faster, that doesn't typically happen when I open up my medicine jar from CO's finest.  I felt the need to smoke less weed today, which is big since I have been doing a little bit of marijuana replacement therapy for no longer being a cigarette smoker.  I was enjoying the laser focus.  No need to summon any energy or motivation to fulfill the daily mission.  It was as simple as thought, to action, with a calm and excited feeling in between.  Almost feels like it's too good to be true.  As of today, I expect the therapeutic effects to grow as mentioned below.  My only concern would be what happens when you stop.  Seems as if this is stage 2 of clinical trials.  I am on Day 1 of Blue's trials    Therapeutic effect Noopepta evident with 5-7 days of treatment, in the form of protivotrevozhnogo and tonic effects. At 7-14 days of therapy, there vegetonormalizuyuschee effect, normalization of sleep. From 14-20 days of therapy revealed a positive effect on cognitive function of the drug, the parameters of attention and memory

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melinde· 10h ago

How do you stomach noopept? I am on about my second gram which I got from a friend who sells it in bulk. It is by far the worst taste I have ever experienced, maybe next to an ayahuasca brew I had. I haven't been taking it for a while just because of the taste. I don't really seem to get any obvious effects

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earnestdeer· 9h ago

How and how much are you dosing?

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melinde· 6h ago

Initially I would keep it under my tongue and wait till it dissolves. Then tried putting it in shakes or honey to ease the taste. Now I just swallow and drink water. Usually I pinch a bit, probably around 200mg

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earnestdeer· 5h ago

No, this is not good.  The daily max is 60 mgs with Noopept.  You can over do it with this nootropic... Be careful axl.  1 gram of Noopept should last you for several weeks. The effects accumulate.    You may just not groove with this nootropic right now.

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