D
duskfall
26 Jul 2026
interesting find
Ibogaine's inactivity at the Serotonin 2 (5HT2) receptor would seem to mean that it can validly be termed the "non-trippy tryptamine." Though persons with heavy prior experience of using of 5HT2 active tryptamines (LSD, DMT, psilocybin, etc.) frequently report trippy effects with ibogaine - (dissolution of previously coherent individuality of the sensory and internal stimuli, presence of non-physical visionary components, etc.) - few people without such history relate the same. With 5HT-2 tryps the ego spaces out, while with ibogaine it sinks down. This would seem to provide marked benefits for long-term psychotherapeutic goals in that ibogaine use seems to gradually lead to ego dissolution and openness, whereas use of 5HT-2 tryps more typically leads to selective openness with some degree of ego-reinforcement, not that the latter doesn't also have potentially beneficial effects.
0